Treatment of locally advanced rectal cancer

RA Klaassen; GAP Nieuwenhuijzen; H Martijn; HJT Rutten; GAP Hospers; T Wiggers

doi:10.1016/j.suronc.2004.08.004

Treatment of locally advanced rectal cancer

RA Klaassen, GAP Nieuwenhuijzen^*, H Martijn, HJT Rutten, GAP Hospers, T Wiggers

^*Corresponding author for this work

Guided Treatment in Optimal Selected Cancer Patients (GUTS)

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Abstract

Historically, locally advanced rectal cancer is known for its dismal prognosis. The treatment of locally advanced rectal cancer is subject to continuous change due to development of new and better diagnostic tools, radiotherapeutic techniques, chemotherapeutic agents and understanding of the subject. It is clear, that a multimodality approach is the only way to achieve satisfactory local recurrence and survival rates in this type of cancer. However, which multimodality strategy is to be used still remains a point of controversy. This review summarises recent developments in imaging, (neo-) adjuvant therapy and surgical techniques in the treatment of primary locally advanced rectal cancer. (C) 2004 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	137-147
Number of pages	11
Journal	Surgical oncology-Oxford
Volume	13
Issue number	2-3
DOIs	https://doi.org/10.1016/j.suronc.2004.08.004
Publication status	Published - 2004

Keywords

rectal cancer
locally advanced
review
multimodality treatment
CIRCUMFERENTIAL MARGIN INVOLVEMENT
INTRAOPERATIVE RADIATION-THERAPY
PHASE-II TRIAL
PREOPERATIVE CHEMORADIATION
NEOADJUVANT CHEMORADIATION
MESORECTAL EXCISION
COMPLETE RESPONSE
RADIOTHERAPY
SURGERY
RESECTION

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title = "Treatment of locally advanced rectal cancer",

abstract = "Historically, locally advanced rectal cancer is known for its dismal prognosis. The treatment of locally advanced rectal cancer is subject to continuous change due to development of new and better diagnostic tools, radiotherapeutic techniques, chemotherapeutic agents and understanding of the subject. It is clear, that a multimodality approach is the only way to achieve satisfactory local recurrence and survival rates in this type of cancer. However, which multimodality strategy is to be used still remains a point of controversy. This review summarises recent developments in imaging, (neo-) adjuvant therapy and surgical techniques in the treatment of primary locally advanced rectal cancer. (C) 2004 Elsevier Ltd. All rights reserved.",

keywords = "rectal cancer, locally advanced, review, multimodality treatment, CIRCUMFERENTIAL MARGIN INVOLVEMENT, INTRAOPERATIVE RADIATION-THERAPY, PHASE-II TRIAL, PREOPERATIVE CHEMORADIATION, NEOADJUVANT CHEMORADIATION, MESORECTAL EXCISION, COMPLETE RESPONSE, RADIOTHERAPY, SURGERY, RESECTION",

author = "RA Klaassen and GAP Nieuwenhuijzen and H Martijn and HJT Rutten and GAP Hospers and T Wiggers",

year = "2004",

doi = "10.1016/j.suronc.2004.08.004",

language = "English",

volume = "13",

pages = "137--147",

journal = "Surgical oncology-Oxford",

issn = "0960-7404",

publisher = "ELSEVIER SCI LTD",

number = "2-3",

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TY - JOUR

T1 - Treatment of locally advanced rectal cancer

AU - Klaassen, RA

AU - Nieuwenhuijzen, GAP

AU - Martijn, H

AU - Rutten, HJT

AU - Hospers, GAP

AU - Wiggers, T

PY - 2004

Y1 - 2004

N2 - Historically, locally advanced rectal cancer is known for its dismal prognosis. The treatment of locally advanced rectal cancer is subject to continuous change due to development of new and better diagnostic tools, radiotherapeutic techniques, chemotherapeutic agents and understanding of the subject. It is clear, that a multimodality approach is the only way to achieve satisfactory local recurrence and survival rates in this type of cancer. However, which multimodality strategy is to be used still remains a point of controversy. This review summarises recent developments in imaging, (neo-) adjuvant therapy and surgical techniques in the treatment of primary locally advanced rectal cancer. (C) 2004 Elsevier Ltd. All rights reserved.

AB - Historically, locally advanced rectal cancer is known for its dismal prognosis. The treatment of locally advanced rectal cancer is subject to continuous change due to development of new and better diagnostic tools, radiotherapeutic techniques, chemotherapeutic agents and understanding of the subject. It is clear, that a multimodality approach is the only way to achieve satisfactory local recurrence and survival rates in this type of cancer. However, which multimodality strategy is to be used still remains a point of controversy. This review summarises recent developments in imaging, (neo-) adjuvant therapy and surgical techniques in the treatment of primary locally advanced rectal cancer. (C) 2004 Elsevier Ltd. All rights reserved.

KW - rectal cancer

KW - locally advanced

KW - review

KW - multimodality treatment

KW - CIRCUMFERENTIAL MARGIN INVOLVEMENT

KW - INTRAOPERATIVE RADIATION-THERAPY

KW - PHASE-II TRIAL

KW - PREOPERATIVE CHEMORADIATION

KW - NEOADJUVANT CHEMORADIATION

KW - MESORECTAL EXCISION

KW - COMPLETE RESPONSE

KW - RADIOTHERAPY

KW - SURGERY

KW - RESECTION

U2 - 10.1016/j.suronc.2004.08.004

DO - 10.1016/j.suronc.2004.08.004

M3 - Article

SN - 0960-7404

VL - 13

SP - 137

EP - 147

JO - Surgical oncology-Oxford

JF - Surgical oncology-Oxford

IS - 2-3

ER -

Treatment of locally advanced rectal cancer

Abstract

Keywords

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