TORPEdO: A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer

David J. Thomson; Clare Cruickshank; Helen Baines; Russell Banner; Matthew Beasley; Guy Betts; Helen Bulbeck; Frances Charlwood; Judith Christian; Matthew Clarke; Olly Donnelly; Bernadette Foran; Callum Gillies; Clare Griffin; Jarrod J. Homer; Johannes A. Langendijk; Lip Wai Lee; James Lester; Matthew Lowe; Andrew McPartlin; Elizabeth Miles; Christopher Nutting; Nachi Palaniappan; Robin Prestwich; James M. Price; Clare Roberts; Justin Roe; Ramkumar Shanmugasundaram; Rita Simões; Anna Thompson; Catharine West; Lorna Wilson; Jane Wolstenholme; Emma Hall

doi:10.1016/j.ctro.2022.11.010

TORPEdO: A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer

David J. Thomson^*, Clare Cruickshank, Helen Baines, Russell Banner, Matthew Beasley, Guy Betts, Helen Bulbeck, Frances Charlwood, Judith Christian, Matthew Clarke, Olly Donnelly, Bernadette Foran, Callum Gillies, Clare Griffin, Jarrod J. Homer, Johannes A. Langendijk, Lip Wai Lee, James Lester, Matthew Lowe, Andrew McPartlinElizabeth Miles, Christopher Nutting, Nachi Palaniappan, Robin Prestwich, James M. Price, Clare Roberts, Justin Roe, Ramkumar Shanmugasundaram, Rita Simões, Anna Thompson, Catharine West, Lorna Wilson, Jane Wolstenholme, Emma Hall

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

14 Citations (Scopus)

150 Downloads (Pure)

Original language	English
Pages (from-to)	147-154
Number of pages	8
Journal	Clinical and Translational Radiation Oncology
Volume	38
DOIs	https://doi.org/10.1016/j.ctro.2022.11.010
Publication status	Published - Jan-2023

Access to Document

10.1016/j.ctro.2022.11.010Licence: CC BY

TORPEdOFinal publisher's version, 2.04 MBLicence: CC BY

Handle.net

Persistent link

Cite this

Thomson, D. J., Cruickshank, C., Baines, H., Banner, R., Beasley, M., Betts, G., Bulbeck, H., Charlwood, F., Christian, J., Clarke, M., Donnelly, O., Foran, B., Gillies, C., Griffin, C., Homer, J. J., Langendijk, J. A., Lee, L. W., Lester, J., Lowe, M., ... Hall, E. (2023). TORPEdO: A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer. Clinical and Translational Radiation Oncology, 38, 147-154. https://doi.org/10.1016/j.ctro.2022.11.010

@article{7def6de8a68e420db656fa1b6ca98080,

title = "TORPEdO: A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer",

author = "Thomson, {David J.} and Clare Cruickshank and Helen Baines and Russell Banner and Matthew Beasley and Guy Betts and Helen Bulbeck and Frances Charlwood and Judith Christian and Matthew Clarke and Olly Donnelly and Bernadette Foran and Callum Gillies and Clare Griffin and Homer, {Jarrod J.} and Langendijk, {Johannes A.} and Lee, {Lip Wai} and James Lester and Matthew Lowe and Andrew McPartlin and Elizabeth Miles and Christopher Nutting and Nachi Palaniappan and Robin Prestwich and Price, {James M.} and Clare Roberts and Justin Roe and Ramkumar Shanmugasundaram and Rita Sim{\~o}es and Anna Thompson and Catharine West and Lorna Wilson and Jane Wolstenholme and Emma Hall",

note = "Funding Information: TORPEdO is funded by Cancer Research UK (CRUK/18/010; A27172). Funding is also received from The Taylor Family Foundation (CRUK/C19941/A30286). Funding Information: The trial is sponsored by The Institute of Cancer Research and centrally managed by The Institute of Cancer Research Clinical Trials and Statistics Unit (ICR-CTSU). TORPEdO is supported by the National Institute for Health Research funded National Radiotherapy Trials Quality Assurance Group (RTTQA). Funding Information: We acknowledge NHS funding to the NIHR Biomedical Research Centre at The Royal Marsden and The Institute of Cancer Research. EH acknowledges support from a Cancer Research UK Network Accelerator Award Grant (A21993) to the Advanced Radiotherapy Network (ART-NET) consortium and Cancer Research UK Clinical Trials Unit core funding to ICR-CTSU (C1491/A15955). ",

year = "2023",

month = jan,

doi = "10.1016/j.ctro.2022.11.010",

language = "English",

volume = "38",

pages = "147--154",

journal = "Clinical and Translational Radiation Oncology",

issn = "2405-6308",

publisher = "Elsevier",

}

Thomson, DJ, Cruickshank, C, Baines, H, Banner, R, Beasley, M, Betts, G, Bulbeck, H, Charlwood, F, Christian, J, Clarke, M, Donnelly, O, Foran, B, Gillies, C, Griffin, C, Homer, JJ, Langendijk, JA, Lee, LW, Lester, J, Lowe, M, McPartlin, A, Miles, E, Nutting, C, Palaniappan, N, Prestwich, R, Price, JM, Roberts, C, Roe, J, Shanmugasundaram, R, Simões, R, Thompson, A, West, C, Wilson, L, Wolstenholme, J & Hall, E 2023, 'TORPEdO: A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer', Clinical and Translational Radiation Oncology, vol. 38, pp. 147-154. https://doi.org/10.1016/j.ctro.2022.11.010

TORPEdO: A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer. / Thomson, David J.; Cruickshank, Clare; Baines, Helen et al.
In: Clinical and Translational Radiation Oncology, Vol. 38, 01.2023, p. 147-154.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - TORPEdO

T2 - A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer

AU - Thomson, David J.

AU - Cruickshank, Clare

AU - Baines, Helen

AU - Banner, Russell

AU - Beasley, Matthew

AU - Betts, Guy

AU - Bulbeck, Helen

AU - Charlwood, Frances

AU - Christian, Judith

AU - Clarke, Matthew

AU - Donnelly, Olly

AU - Foran, Bernadette

AU - Gillies, Callum

AU - Griffin, Clare

AU - Homer, Jarrod J.

AU - Langendijk, Johannes A.

AU - Lee, Lip Wai

AU - Lester, James

AU - Lowe, Matthew

AU - McPartlin, Andrew

AU - Miles, Elizabeth

AU - Nutting, Christopher

AU - Palaniappan, Nachi

AU - Prestwich, Robin

AU - Price, James M.

AU - Roberts, Clare

AU - Roe, Justin

AU - Shanmugasundaram, Ramkumar

AU - Simões, Rita

AU - Thompson, Anna

AU - West, Catharine

AU - Wilson, Lorna

AU - Wolstenholme, Jane

AU - Hall, Emma

N1 - Funding Information: TORPEdO is funded by Cancer Research UK (CRUK/18/010; A27172). Funding is also received from The Taylor Family Foundation (CRUK/C19941/A30286). Funding Information: The trial is sponsored by The Institute of Cancer Research and centrally managed by The Institute of Cancer Research Clinical Trials and Statistics Unit (ICR-CTSU). TORPEdO is supported by the National Institute for Health Research funded National Radiotherapy Trials Quality Assurance Group (RTTQA). Funding Information: We acknowledge NHS funding to the NIHR Biomedical Research Centre at The Royal Marsden and The Institute of Cancer Research. EH acknowledges support from a Cancer Research UK Network Accelerator Award Grant (A21993) to the Advanced Radiotherapy Network (ART-NET) consortium and Cancer Research UK Clinical Trials Unit core funding to ICR-CTSU (C1491/A15955).

PY - 2023/1

Y1 - 2023/1

U2 - 10.1016/j.ctro.2022.11.010

DO - 10.1016/j.ctro.2022.11.010

M3 - Article

AN - SCOPUS:85142505287

SN - 2405-6308

VL - 38

SP - 147

EP - 154

JO - Clinical and Translational Radiation Oncology

JF - Clinical and Translational Radiation Oncology

ER -