The large first periplasmic loop of SecD and SecF plays an important role in SecDF functioning

N Nouwen*, M Piwowarek, G Berrelkamp, AJM Driessen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

34 Citations (Scopus)
238 Downloads (Pure)

Abstract

A remarkable feature of proteins of the SecD and SecF family involved in protein translocation is that they possess a very large first periplasmic domain. Here we report that this large first periplasmic domain is not required for the SecD-SecF interaction but that it is important for catalyzing protein translocation.

Original languageEnglish
Pages (from-to)5857-5860
Number of pages4
JournalJournal of Bacteriology
Volume187
Issue number16
DOIs
Publication statusPublished - Aug-2005

Keywords

  • PROTEIN TRANSLOCATION MACHINERY
  • ESCHERICHIA-COLI
  • MEMBRANE
  • YIDC
  • RECONSTITUTION
  • COMPONENTS
  • COMPLEX

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