The Added Value of [18F]FDG PET/CT in the Management of Invasive Fungal Infections

Alfred O Ankrah*, Dina Creemers-Schild, Bart de Keizer, Hans C Klein, Rudi A J O Dierckx, Thomas C Kwee, Lambert F R Span, Pim A de Jong, Mike M Sathekge, Andor W J M Glaudemans

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)
103 Downloads (Pure)

Abstract

Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [18F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [18F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented for each procedure. We included 155 [18F]FDG PET/CT scans performed in 73 patients. A total of 216 anatomy-based studies including 80 chest X-rays, 89 computed tomography studies, 14 magnetic resonance imaging studies, and 33 ultrasound imaging studies were studied. The anatomy-based studies were concordant with the [18F]FDG PET/CT for 94.4% of the scans performed. [18F]FDG PET/CT detected IFI lesions outside of the areas imaged by the anatomy-based studies in 48.6% of the scans. In 74% of the patients, [18F]FDG PET/CT added value in the management of the IFIs.

Original languageEnglish
Article number137
Number of pages13
JournalDiagnostics
Volume11
Issue number1
DOIs
Publication statusPublished - 17-Jan-2021

Fingerprint

Dive into the research topics of 'The Added Value of [18F]FDG PET/CT in the Management of Invasive Fungal Infections'. Together they form a unique fingerprint.

Cite this