Reversible regulation of metallo-base-pair interactions for DNA dehybridization by ultrasound

Shuaidong Huo, Yu Zhou, Zhihuan Liao, Pengkun Zhao, Miancheng Zou, Robert Göstl, Andreas Herrmann*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
127 Downloads (Pure)

Abstract

Mechanical force applied by ultrasound in solution leads to the dissociation of DNA metallo-base-pair interactions when these motifs are functionalized with oligodeoxynucleotide sequences of sufficient length. The annealing and force-induced denaturing process is followed by the attachment of distance-sensitive fluorescent probes and is found to be reversible.

Original languageEnglish
Pages (from-to)7438-7440
Number of pages3
JournalChemical Communications
Volume57
Issue number60
DOIs
Publication statusPublished - 4-Aug-2021

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