Post-surgical use of radioiodine (I-131) in patients with papillary and follicular thyroid cancer and the issue of remnant ablation: A consensus report

F Pacini; M Schlumberger; C Harmer; GG Berg; O Cohen; L Duntas; F Jamar; B Jarzab; E Limbert; P Lind; C Reiners; FS Franco; J Smit; W Wiersinga

doi:10.1530/eje.1.02014

Post-surgical use of radioiodine (I-131) in patients with papillary and follicular thyroid cancer and the issue of remnant ablation: A consensus report

F Pacini^*, M Schlumberger, C Harmer, GG Berg, O Cohen, L Duntas, F Jamar, B Jarzab, E Limbert, P Lind, C Reiners, FS Franco, J Smit, W Wiersinga

^*Corresponding author for this work

University of Groningen

Research output: Contribution to journal › Article › Academic › peer-review

164 Citations (Scopus)

Abstract

Objective: To determine, based on published literature and expert clinical experience. current indications for the post-surgical administration of a large radioiodine activity in patients with differentiated thyroid cancer.

Design and methods: A literature review was performed and was then analyzed and discussed by a panel of experts from 13 European countries.

Results: There is general agreement that patients with unifocal microcarcinomas = 1 cm in diameter and no node or distant metastases have a

Conclusion: This survey confirms that post-surgical radioiodinc should be used selectively. The modality is definitely indicated in patients with distant metastases. incomplete tumor resection, or complete tumor resection but high risk of recurrence and mortality. Probable indications include patients with tumors > 1 cm and with suboptimal surgery (less than total thyroidectomy or no lymph node dissection), with age <16 years, or with unfavorable histology.

Original language	English
Pages (from-to)	651-659
Number of pages	9
Journal	European Journal of Endocrinology
Volume	153
Issue number	5
DOIs	https://doi.org/10.1530/eje.1.02014
Publication status	Published - Nov-2005

Keywords

SERUM THYROGLOBULIN LEVELS
RECOMBINANT HUMAN TSH
RANDOMIZED CLINICAL-TRIAL
LOW-RISK PATIENTS
RADIOACTIVE IODINE
FOLLOW-UP
HORMONE WITHDRAWAL
NECK ULTRASONOGRAPHY
STIMULATED SERUM
PREDICTIVE-VALUE

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Pacini, F., Schlumberger, M., Harmer, C., Berg, GG., Cohen, O., Duntas, L., Jamar, F., Jarzab, B., Limbert, E., Lind, P., Reiners, C., Franco, FS., Smit, J., & Wiersinga, W. (2005). Post-surgical use of radioiodine (I-131) in patients with papillary and follicular thyroid cancer and the issue of remnant ablation: A consensus report. European Journal of Endocrinology, 153(5), 651-659. https://doi.org/10.1530/eje.1.02014

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title = "Post-surgical use of radioiodine (I-131) in patients with papillary and follicular thyroid cancer and the issue of remnant ablation: A consensus report",

abstract = "Objective: To determine, based on published literature and expert clinical experience. current indications for the post-surgical administration of a large radioiodine activity in patients with differentiated thyroid cancer.Design and methods: A literature review was performed and was then analyzed and discussed by a panel of experts from 13 European countries.Results: There is general agreement that patients with unifocal microcarcinomas = 1 cm in diameter and no node or distant metastases have aConclusion: This survey confirms that post-surgical radioiodinc should be used selectively. The modality is definitely indicated in patients with distant metastases. incomplete tumor resection, or complete tumor resection but high risk of recurrence and mortality. Probable indications include patients with tumors > 1 cm and with suboptimal surgery (less than total thyroidectomy or no lymph node dissection), with age <16 years, or with unfavorable histology.",

keywords = "SERUM THYROGLOBULIN LEVELS, RECOMBINANT HUMAN TSH, RANDOMIZED CLINICAL-TRIAL, LOW-RISK PATIENTS, RADIOACTIVE IODINE, FOLLOW-UP, HORMONE WITHDRAWAL, NECK ULTRASONOGRAPHY, STIMULATED SERUM, PREDICTIVE-VALUE",

author = "F Pacini and M Schlumberger and C Harmer and GG Berg and O Cohen and L Duntas and F Jamar and B Jarzab and E Limbert and P Lind and C Reiners and FS Franco and J Smit and W Wiersinga",

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Pacini, F, Schlumberger, M, Harmer, C, Berg, GG, Cohen, O, Duntas, L, Jamar, F, Jarzab, B, Limbert, E, Lind, P, Reiners, C, Franco, FS, Smit, J & Wiersinga, W 2005, 'Post-surgical use of radioiodine (I-131) in patients with papillary and follicular thyroid cancer and the issue of remnant ablation: A consensus report', European Journal of Endocrinology, vol. 153, no. 5, pp. 651-659. https://doi.org/10.1530/eje.1.02014

TY - JOUR

T1 - Post-surgical use of radioiodine (I-131) in patients with papillary and follicular thyroid cancer and the issue of remnant ablation

T2 - A consensus report

AU - Pacini, F

AU - Schlumberger, M

AU - Harmer, C

AU - Berg, GG

AU - Cohen, O

AU - Duntas, L

AU - Jamar, F

AU - Jarzab, B

AU - Limbert, E

AU - Lind, P

AU - Reiners, C

AU - Franco, FS

AU - Smit, J

AU - Wiersinga, W

PY - 2005/11

Y1 - 2005/11

N2 - Objective: To determine, based on published literature and expert clinical experience. current indications for the post-surgical administration of a large radioiodine activity in patients with differentiated thyroid cancer.Design and methods: A literature review was performed and was then analyzed and discussed by a panel of experts from 13 European countries.Results: There is general agreement that patients with unifocal microcarcinomas = 1 cm in diameter and no node or distant metastases have aConclusion: This survey confirms that post-surgical radioiodinc should be used selectively. The modality is definitely indicated in patients with distant metastases. incomplete tumor resection, or complete tumor resection but high risk of recurrence and mortality. Probable indications include patients with tumors > 1 cm and with suboptimal surgery (less than total thyroidectomy or no lymph node dissection), with age <16 years, or with unfavorable histology.

AB - Objective: To determine, based on published literature and expert clinical experience. current indications for the post-surgical administration of a large radioiodine activity in patients with differentiated thyroid cancer.Design and methods: A literature review was performed and was then analyzed and discussed by a panel of experts from 13 European countries.Results: There is general agreement that patients with unifocal microcarcinomas = 1 cm in diameter and no node or distant metastases have aConclusion: This survey confirms that post-surgical radioiodinc should be used selectively. The modality is definitely indicated in patients with distant metastases. incomplete tumor resection, or complete tumor resection but high risk of recurrence and mortality. Probable indications include patients with tumors > 1 cm and with suboptimal surgery (less than total thyroidectomy or no lymph node dissection), with age <16 years, or with unfavorable histology.

KW - SERUM THYROGLOBULIN LEVELS

KW - RECOMBINANT HUMAN TSH

KW - RANDOMIZED CLINICAL-TRIAL

KW - LOW-RISK PATIENTS

KW - RADIOACTIVE IODINE

KW - FOLLOW-UP

KW - HORMONE WITHDRAWAL

KW - NECK ULTRASONOGRAPHY

KW - STIMULATED SERUM

KW - PREDICTIVE-VALUE

U2 - 10.1530/eje.1.02014

DO - 10.1530/eje.1.02014

M3 - Article

SN - 0804-4643

VL - 153

SP - 651

EP - 659

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

IS - 5

ER -

Post-surgical use of radioiodine (I-131) in patients with papillary and follicular thyroid cancer and the issue of remnant ablation: A consensus report

Abstract

Keywords

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