MitraClip (R) therapy in patients with end-stage systolic heart failure

Olaf Franzen*, Jan van der Heyden, Stephan Baldus, Michael Schlueter, Wolfgang Schillinger, Christian Butter, Rainer Hoffmann, Roberto Corti, Giovanni Pedrazzini, Martin J. Swaans, Michael Neuss, Volker Rudolph, Daniel Suerder, Juerg Gruenenfelder, Christine Eulenburg, Hermann Reichenspurner, Thomas Meinertz, Angelo Auricchio

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

277 Citations (Scopus)

Abstract

Aims To assess the feasibility, short-term durability and clinical outcomes of MitraClip (R) therapy for mitral regurgitation (MR) in patients with end-stage heart failure and a severely reduced left ventricular (LV) ejection fraction.

Methods and results We analysed retrospectively collected data from seven European centres. Included in the study were 50 heart failure patients [ mean age 70 +/- 11 years, 38 men (76%)] with a LV ejection fraction

Conclusion MitraClip (R) therapy reduces functional MR in patients with end-stage heart failure and marked LV dysfunction and entails clinical benefit at 6 months.

Original languageEnglish
Pages (from-to)569-576
Number of pages8
JournalEuropean Journal of Heart Failure
Volume13
Issue number5
DOIs
Publication statusPublished - May-2011
Externally publishedYes

Keywords

  • Heart failure
  • Heart valves
  • Mitral regurgitation
  • Catheter-based therapy
  • ISCHEMIC MITRAL REGURGITATION
  • CARDIAC RESYNCHRONIZATION THERAPY
  • VALVE ANNULOPLASTY
  • CLINICAL-TRIAL
  • SEVERITY
  • IMPACT
  • DYSFUNCTION
  • REPAIR
  • ECHOCARDIOGRAPHY
  • RISK

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