Initiated CVD of poly(2-hydroxyethyl methacrylate) hydrogels: Synthesis, characterization and in-vitro biocompatibility

Ranjita K. Bose; Kenneth K.S. Lau

doi:10.1002/cvde.200806748

Initiated CVD of poly(2-hydroxyethyl methacrylate) hydrogels: Synthesis, characterization and in-vitro biocompatibility

Ranjita K. Bose, Kenneth K.S. Lau

Research output: Contribution to journal › Article › Academic › peer-review

37 Citations (Scopus)

Abstract

Initiated (i)CVD, an all-dry, one-step surface polymerization technique, was used to synthesize thin film hydrogels of poly (2-hydroxyethyl methacrylate) (PHEMA). Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopies showed stoichiometric PHEMA films obtained by iCVD. Differential scanning calorimetry (DSC) revealed a high glass transition temperature, indicative of high molecular mass polymer. In-vitro cell studies using adult human dermal fibroblasts (HDF) demonstrated the nontoxic nature and good cell adhesion properties of iCVD PHEMA films.

Original language	English
Pages (from-to)	150-155
Number of pages	6
Journal	Chemical Vapor Deposition
Volume	15
Issue number	4-6
DOIs	https://doi.org/10.1002/cvde.200806748
Publication status	Published - Jun-2009
Externally published	Yes

Keywords

Cell adhesion
Cytotoxicity
Hydrogel
Initiated CVD
PHE

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title = "Initiated CVD of poly(2-hydroxyethyl methacrylate) hydrogels: Synthesis, characterization and in-vitro biocompatibility",

abstract = "Initiated (i)CVD, an all-dry, one-step surface polymerization technique, was used to synthesize thin film hydrogels of poly (2-hydroxyethyl methacrylate) (PHEMA). Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopies showed stoichiometric PHEMA films obtained by iCVD. Differential scanning calorimetry (DSC) revealed a high glass transition temperature, indicative of high molecular mass polymer. In-vitro cell studies using adult human dermal fibroblasts (HDF) demonstrated the nontoxic nature and good cell adhesion properties of iCVD PHEMA films.",

keywords = "Cell adhesion, Cytotoxicity, Hydrogel, Initiated CVD, PHE",

author = "Bose, {Ranjita K.} and Lau, {Kenneth K.S.}",

year = "2009",

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language = "English",

volume = "15",

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journal = "Chemical Vapor Deposition",

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T2 - Synthesis, characterization and in-vitro biocompatibility

AU - Bose, Ranjita K.

AU - Lau, Kenneth K.S.

PY - 2009/6

Y1 - 2009/6

N2 - Initiated (i)CVD, an all-dry, one-step surface polymerization technique, was used to synthesize thin film hydrogels of poly (2-hydroxyethyl methacrylate) (PHEMA). Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopies showed stoichiometric PHEMA films obtained by iCVD. Differential scanning calorimetry (DSC) revealed a high glass transition temperature, indicative of high molecular mass polymer. In-vitro cell studies using adult human dermal fibroblasts (HDF) demonstrated the nontoxic nature and good cell adhesion properties of iCVD PHEMA films.

AB - Initiated (i)CVD, an all-dry, one-step surface polymerization technique, was used to synthesize thin film hydrogels of poly (2-hydroxyethyl methacrylate) (PHEMA). Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopies showed stoichiometric PHEMA films obtained by iCVD. Differential scanning calorimetry (DSC) revealed a high glass transition temperature, indicative of high molecular mass polymer. In-vitro cell studies using adult human dermal fibroblasts (HDF) demonstrated the nontoxic nature and good cell adhesion properties of iCVD PHEMA films.

KW - Cell adhesion

KW - Cytotoxicity

KW - Hydrogel

KW - Initiated CVD

KW - PHE

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AN - SCOPUS:67650340978

SN - 0948-1907

VL - 15

SP - 150

EP - 155

JO - Chemical Vapor Deposition

JF - Chemical Vapor Deposition

IS - 4-6

ER -

Initiated CVD of poly(2-hydroxyethyl methacrylate) hydrogels: Synthesis, characterization and in-vitro biocompatibility

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