Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours

Audrey Nailor; David A. Walker; Thomas S. Jacques; Kathy E. Warren; Henry Brem; Pamela R. Kearns; John Greenwood; Jeffrey I. Penny; Geoffrey J. Pilkington; Angel M. Carcaboso; Gudrun Fleischhack; Donald Macarthur; Irene Slavc; Lisethe Meijer; Steven Gill; Stephen Lowis; Dannis G. van Vuurden; Monica S. Pearl; Steven C. Clifford; Sorana Morrissy; Delyan P. Ivanov; Kevin Beccaria; Richard J. Gilbertson; Karin Straathof; Jordan J. Green; Stuart Smith; Ruman Rahman; John-Paul Kilday

doi:10.3332/ecancer.2016.630

Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours

Audrey Nailor^*, David A. Walker, Thomas S. Jacques, Kathy E. Warren, Henry Brem, Pamela R. Kearns, John Greenwood, Jeffrey I. Penny, Geoffrey J. Pilkington, Angel M. Carcaboso, Gudrun Fleischhack, Donald Macarthur, Irene Slavc, Lisethe Meijer, Steven Gill, Stephen Lowis, Dannis G. van Vuurden, Monica S. Pearl, Steven C. Clifford, Sorana MorrissyDelyan P. Ivanov, Kevin Beccaria, Richard J. Gilbertson, Karin Straathof, Jordan J. Green, Stuart Smith, Ruman Rahman, John-Paul Kilday

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

The first Workshop on Drug Delivery in Paediatric Brain Tumours was hosted in London by the charity Children with Cancer UK. The goals of the workshop were to break down the barriers to treating central nervous system (CNS) tumours in children, leading to new collaborations and further innovations in this under-represented and emotive field. These barriers include the physical delivery challenges presented by the blood-brain barrier, the underpinning reasons for the intractability of CNS cancers, and the practical difficulties of delivering cancer treatment to the brains of children. Novel techniques for overcoming these problems were discussed, new models brought forth, and experiences compared.

Original language	English
Article number	630
Number of pages	13
Journal	Ecancermedicalscience
Volume	10
DOIs	https://doi.org/10.3332/ecancer.2016.630
Publication status	Published - 31-Mar-2016

Keywords

drug delivery
translational medicine
paediatrics
brain tumours
glioma
medulloblastoma
CNS involvement
blood-brain barrier

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Highlights of Children with Cancer UK’s Workshop on Drug Delivery in Paediatric Brain TumoursFinal publisher's version, 423 KBLicence: CC BY

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Nailor, A., Walker, D. A., Jacques, T. S., Warren, K. E., Brem, H., Kearns, P. R., Greenwood, J., Penny, J. I., Pilkington, G. J., Carcaboso, A. M., Fleischhack, G., Macarthur, D., Slavc, I., Meijer, L., Gill, S., Lowis, S., van Vuurden, D. G., Pearl, M. S., Clifford, S. C., ... Kilday, J.-P. (2016). Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours. Ecancermedicalscience, 10, Article 630. https://doi.org/10.3332/ecancer.2016.630

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title = "Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours",

abstract = "The first Workshop on Drug Delivery in Paediatric Brain Tumours was hosted in London by the charity Children with Cancer UK. The goals of the workshop were to break down the barriers to treating central nervous system (CNS) tumours in children, leading to new collaborations and further innovations in this under-represented and emotive field. These barriers include the physical delivery challenges presented by the blood-brain barrier, the underpinning reasons for the intractability of CNS cancers, and the practical difficulties of delivering cancer treatment to the brains of children. Novel techniques for overcoming these problems were discussed, new models brought forth, and experiences compared.",

keywords = "drug delivery, translational medicine, paediatrics, brain tumours, glioma, medulloblastoma, CNS involvement, blood-brain barrier",

author = "Audrey Nailor and Walker, {David A.} and Jacques, {Thomas S.} and Warren, {Kathy E.} and Henry Brem and Kearns, {Pamela R.} and John Greenwood and Penny, {Jeffrey I.} and Pilkington, {Geoffrey J.} and Carcaboso, {Angel M.} and Gudrun Fleischhack and Donald Macarthur and Irene Slavc and Lisethe Meijer and Steven Gill and Stephen Lowis and {van Vuurden}, {Dannis G.} and Pearl, {Monica S.} and Clifford, {Steven C.} and Sorana Morrissy and Ivanov, {Delyan P.} and Kevin Beccaria and Gilbertson, {Richard J.} and Karin Straathof and Green, {Jordan J.} and Stuart Smith and Ruman Rahman and John-Paul Kilday",

year = "2016",

month = mar,

day = "31",

doi = "10.3332/ecancer.2016.630",

language = "English",

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Nailor, A, Walker, DA, Jacques, TS, Warren, KE, Brem, H, Kearns, PR, Greenwood, J, Penny, JI, Pilkington, GJ, Carcaboso, AM, Fleischhack, G, Macarthur, D, Slavc, I, Meijer, L, Gill, S, Lowis, S, van Vuurden, DG, Pearl, MS, Clifford, SC, Morrissy, S, Ivanov, DP, Beccaria, K, Gilbertson, RJ, Straathof, K, Green, JJ, Smith, S, Rahman, R & Kilday, J-P 2016, 'Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours', Ecancermedicalscience, vol. 10, 630. https://doi.org/10.3332/ecancer.2016.630

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AU - Nailor, Audrey

AU - Walker, David A.

AU - Jacques, Thomas S.

AU - Warren, Kathy E.

AU - Brem, Henry

AU - Kearns, Pamela R.

AU - Greenwood, John

AU - Penny, Jeffrey I.

AU - Pilkington, Geoffrey J.

AU - Carcaboso, Angel M.

AU - Fleischhack, Gudrun

AU - Macarthur, Donald

AU - Slavc, Irene

AU - Meijer, Lisethe

AU - Gill, Steven

AU - Lowis, Stephen

AU - van Vuurden, Dannis G.

AU - Pearl, Monica S.

AU - Clifford, Steven C.

AU - Morrissy, Sorana

AU - Ivanov, Delyan P.

AU - Beccaria, Kevin

AU - Gilbertson, Richard J.

AU - Straathof, Karin

AU - Green, Jordan J.

AU - Smith, Stuart

AU - Rahman, Ruman

AU - Kilday, John-Paul

PY - 2016/3/31

Y1 - 2016/3/31

N2 - The first Workshop on Drug Delivery in Paediatric Brain Tumours was hosted in London by the charity Children with Cancer UK. The goals of the workshop were to break down the barriers to treating central nervous system (CNS) tumours in children, leading to new collaborations and further innovations in this under-represented and emotive field. These barriers include the physical delivery challenges presented by the blood-brain barrier, the underpinning reasons for the intractability of CNS cancers, and the practical difficulties of delivering cancer treatment to the brains of children. Novel techniques for overcoming these problems were discussed, new models brought forth, and experiences compared.

AB - The first Workshop on Drug Delivery in Paediatric Brain Tumours was hosted in London by the charity Children with Cancer UK. The goals of the workshop were to break down the barriers to treating central nervous system (CNS) tumours in children, leading to new collaborations and further innovations in this under-represented and emotive field. These barriers include the physical delivery challenges presented by the blood-brain barrier, the underpinning reasons for the intractability of CNS cancers, and the practical difficulties of delivering cancer treatment to the brains of children. Novel techniques for overcoming these problems were discussed, new models brought forth, and experiences compared.

KW - drug delivery

KW - translational medicine

KW - paediatrics

KW - brain tumours

KW - glioma

KW - medulloblastoma

KW - CNS involvement

KW - blood-brain barrier

U2 - 10.3332/ecancer.2016.630

DO - 10.3332/ecancer.2016.630

M3 - Article

SN - 1754-6605

VL - 10

JO - Ecancermedicalscience

JF - Ecancermedicalscience

M1 - 630

ER -

Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours

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