DRUG OR TOOL, DESIGN OR SERENDIPITY

CLMJ VERLINDE; BW DIJKSTRA

DRUG OR TOOL, DESIGN OR SERENDIPITY

CLMJ VERLINDE^*, BW DIJKSTRA

^*Corresponding author for this work

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

3 Citations (Scopus)

Abstract

Iterative protein structure-based ligand design has led to a 'selective' inhibitor of human nonpancreatic secretory phospholipase A(2) which provides a new tool for probing metabolic pathways and may lead to a useful drug.

Original language	English
Pages (from-to)	429-432
Number of pages	4
Journal	Nature Structural Biology
Volume	2
Issue number	6
Publication status	Published - Jun-1995

Keywords

SYNOVIAL-FLUID PHOSPHOLIPASE-A2
INDOMETHACIN
RESOLUTION

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@article{1fa9fdc15d5640b0be129273275920bb,

title = "DRUG OR TOOL, DESIGN OR SERENDIPITY",

abstract = "Iterative protein structure-based ligand design has led to a 'selective' inhibitor of human nonpancreatic secretory phospholipase A(2) which provides a new tool for probing metabolic pathways and may lead to a useful drug.",

keywords = "SYNOVIAL-FLUID PHOSPHOLIPASE-A2, INDOMETHACIN, RESOLUTION",

author = "CLMJ VERLINDE and BW DIJKSTRA",

year = "1995",

month = jun,

language = "English",

volume = "2",

pages = "429--432",

journal = "Nature Structural Biology",

issn = "1072-8368",

number = "6",

}

TY - JOUR

T1 - DRUG OR TOOL, DESIGN OR SERENDIPITY

AU - VERLINDE, CLMJ

AU - DIJKSTRA, BW

PY - 1995/6

Y1 - 1995/6

N2 - Iterative protein structure-based ligand design has led to a 'selective' inhibitor of human nonpancreatic secretory phospholipase A(2) which provides a new tool for probing metabolic pathways and may lead to a useful drug.

AB - Iterative protein structure-based ligand design has led to a 'selective' inhibitor of human nonpancreatic secretory phospholipase A(2) which provides a new tool for probing metabolic pathways and may lead to a useful drug.

KW - SYNOVIAL-FLUID PHOSPHOLIPASE-A2

KW - INDOMETHACIN

KW - RESOLUTION

M3 - Comment/Letter to the editor

SN - 1072-8368

VL - 2

SP - 429

EP - 432

JO - Nature Structural Biology

JF - Nature Structural Biology

IS - 6

ER -

DRUG OR TOOL, DESIGN OR SERENDIPITY

Abstract

Keywords

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