Bridging between Organocatalysis and Biocatalysis: Asymmetric Addition of Acetaldehyde to ss-Nitrostyrenes Catalyzed by a Promiscuous Proline-Based Tautomerase

Ellen Zandvoort; Edzard M. Geertsema; Bert-Jan Baas; Wim J. Quax; Gerrit J. Poelarends

doi:10.1002/anie.201107404

Bridging between Organocatalysis and Biocatalysis: Asymmetric Addition of Acetaldehyde to ss-Nitrostyrenes Catalyzed by a Promiscuous Proline-Based Tautomerase

Ellen Zandvoort, Edzard M. Geertsema, Bert-Jan Baas, Wim J. Quax, Gerrit J. Poelarends^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

76 Citations (Scopus)

Original language	English
Pages (from-to)	1240-1243
Number of pages	4
Journal	Angewandte Chemie-International Edition
Volume	51
Issue number	5
DOIs	https://doi.org/10.1002/anie.201107404
Publication status	Published - 2012

Keywords

catalytic promiscuity
enzyme catalysis
Michael addition
organocatalysis
tautomerases
ENANTIOSELECTIVE MICHAEL ADDITION
CARBON BOND FORMATION
4-OXALOCROTONATE TAUTOMERASE
MANNICH REACTION
ALDEHYDES
ALDOL
SUPERFAMILY
MALONATE
ENZYMES
KETONES

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Bridging between Organocatalysis and Biocatalysis Asymmetric Addition
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76 Citations
1 Erratum

Erratum: Bridging between organocatalysis and biocatalysis: Asymmetric addition of acetaldehyde to β-nitrostyrenes catalyzed by a promiscuous proline-based tautomerase (Angewandte Chemie - International Edition (2012) 51 (1240-1243) DOI: 10.1002/anie.201107404)
Zandvoort, E., Geertsema, E. M., Baas, B. J., Quax, W. J. & Poelarends, G. J., 18-Jun-2012, In: Angewandte Chemie - International Edition. 51, 25, p. 6035 1 p.
Research output: Contribution to journal › Erratum

1 Citation (Scopus)

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@article{5df5b716d02746378926a7c0a185eff1,

title = "Bridging between Organocatalysis and Biocatalysis: Asymmetric Addition of Acetaldehyde to ss-Nitrostyrenes Catalyzed by a Promiscuous Proline-Based Tautomerase",

keywords = "catalytic promiscuity, enzyme catalysis, Michael addition, organocatalysis, tautomerases, ENANTIOSELECTIVE MICHAEL ADDITION, CARBON BOND FORMATION, 4-OXALOCROTONATE TAUTOMERASE, MANNICH REACTION, ALDEHYDES, ALDOL, SUPERFAMILY, MALONATE, ENZYMES, KETONES",

author = "Ellen Zandvoort and Geertsema, {Edzard M.} and Bert-Jan Baas and Quax, {Wim J.} and Poelarends, {Gerrit J.}",

year = "2012",

doi = "10.1002/anie.201107404",

language = "English",

volume = "51",

pages = "1240--1243",

journal = "Angewandte Chemie-International Edition",

issn = "1433-7851",

publisher = "WILEY-V C H VERLAG GMBH",

number = "5",

}

Bridging between Organocatalysis and Biocatalysis: Asymmetric Addition of Acetaldehyde to ss-Nitrostyrenes Catalyzed by a Promiscuous Proline-Based Tautomerase. / Zandvoort, Ellen; Geertsema, Edzard M.; Baas, Bert-Jan et al.
In: Angewandte Chemie-International Edition, Vol. 51, No. 5, 2012, p. 1240-1243.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Bridging between Organocatalysis and Biocatalysis

T2 - Asymmetric Addition of Acetaldehyde to ss-Nitrostyrenes Catalyzed by a Promiscuous Proline-Based Tautomerase

AU - Zandvoort, Ellen

AU - Geertsema, Edzard M.

AU - Baas, Bert-Jan

AU - Quax, Wim J.

AU - Poelarends, Gerrit J.

PY - 2012

Y1 - 2012

KW - catalytic promiscuity

KW - enzyme catalysis

KW - Michael addition

KW - organocatalysis

KW - tautomerases

KW - ENANTIOSELECTIVE MICHAEL ADDITION

KW - CARBON BOND FORMATION

KW - 4-OXALOCROTONATE TAUTOMERASE

KW - MANNICH REACTION

KW - ALDEHYDES

KW - ALDOL

KW - SUPERFAMILY

KW - MALONATE

KW - ENZYMES

KW - KETONES

U2 - 10.1002/anie.201107404

DO - 10.1002/anie.201107404

M3 - Article

SN - 1433-7851

VL - 51

SP - 1240

EP - 1243

JO - Angewandte Chemie-International Edition

JF - Angewandte Chemie-International Edition

IS - 5

ER -

Bridging between Organocatalysis and Biocatalysis: Asymmetric Addition of Acetaldehyde to ss-Nitrostyrenes Catalyzed by a Promiscuous Proline-Based Tautomerase

Keywords

Access to Document

Handle.net

Embargoed Document

Research output

Erratum: Bridging between organocatalysis and biocatalysis: Asymmetric addition of acetaldehyde to β-nitrostyrenes catalyzed by a promiscuous proline-based tautomerase (Angewandte Chemie - International Edition (2012) 51 (1240-1243) DOI: 10.1002/anie.201107404)

Cite this