Abstract
Recent studies implicate insular cortex and the hormone cortisol in Parkinsonian features. Dopaminergic alterations at the level of the insula may be involved in changes in personality (i.e. novelty seeking) and symptoms of hemispatial neglect. I discuss this evidence and suggest that attention in future research to a possible role of the insula and of cortisol in Parkinsonian features may yield valuable information regarding Parkinson's disease. (c) 2006 Elsevier Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 467-471 |
Number of pages | 5 |
Journal | Parkinsonism & Related Disorders |
Volume | 12 |
Issue number | 8 |
DOIs | |
Publication status | Published - 2006 |
Keywords
- Parkinson
- insula
- cortisol
- turning behavior
- neglect
- novelty seeking
- FACIAL EXPRESSION RECOGNITION
- NOVELTY SEEKING
- NEURAL BASIS
- DISEASE
- PERSONALITY
- DOPAMINE
- PAIN
- TOMOGRAPHY
- RECEPTORS
- BEHAVIOR