Application of nitric oxide measurements in clinical conditions beyond asthma

Andrei Malinovschi; Dora Ludviksdottir; Ellen Tufvesson; Giovanni Rolla; Leif Bjermer; Kjell Alving; Zuzana Diamant

doi:10.3402/ecrj.v2.28517

Application of nitric oxide measurements in clinical conditions beyond asthma

Andrei Malinovschi^*, Dora Ludviksdottir, Ellen Tufvesson, Giovanni Rolla, Leif Bjermer, Kjell Alving, Zuzana Diamant

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

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Abstract

Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in several asthma phenotypes. More recently, FeNO has been evaluated in several other respiratory, infectious, and/or immunological conditions. In this short review, we provide an overview of several clinical studies and discuss the status of potential applications of NO measurements in clinical conditions beyond asthma.

Original language	English
Article number	28517
Number of pages	10
Journal	European clinical respiratory journal
Volume	2
Issue number	1
DOIs	https://doi.org/10.3402/ecrj.v2.28517
Publication status	Published - 2015

Keywords

exhaled nitric oxide
allergic rhinitis
COPD
cystic fibrosis
bronchopulmonary dysplasia
respiratory infections
pulmonary hypertension
hepatopulmonary syndrome
scleroderma
allograft rejections

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title = "Application of nitric oxide measurements in clinical conditions beyond asthma",

abstract = "Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in several asthma phenotypes. More recently, FeNO has been evaluated in several other respiratory, infectious, and/or immunological conditions. In this short review, we provide an overview of several clinical studies and discuss the status of potential applications of NO measurements in clinical conditions beyond asthma.",

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T1 - Application of nitric oxide measurements in clinical conditions beyond asthma

AU - Malinovschi, Andrei

AU - Ludviksdottir, Dora

AU - Tufvesson, Ellen

AU - Rolla, Giovanni

AU - Bjermer, Leif

AU - Alving, Kjell

AU - Diamant, Zuzana

PY - 2015

Y1 - 2015

N2 - Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in several asthma phenotypes. More recently, FeNO has been evaluated in several other respiratory, infectious, and/or immunological conditions. In this short review, we provide an overview of several clinical studies and discuss the status of potential applications of NO measurements in clinical conditions beyond asthma.

AB - Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in several asthma phenotypes. More recently, FeNO has been evaluated in several other respiratory, infectious, and/or immunological conditions. In this short review, we provide an overview of several clinical studies and discuss the status of potential applications of NO measurements in clinical conditions beyond asthma.

KW - exhaled nitric oxide

KW - allergic rhinitis

KW - COPD

KW - cystic fibrosis

KW - bronchopulmonary dysplasia

KW - respiratory infections

KW - pulmonary hypertension

KW - hepatopulmonary syndrome

KW - scleroderma

KW - allograft rejections

U2 - 10.3402/ecrj.v2.28517

DO - 10.3402/ecrj.v2.28517

M3 - Review article

SN - 2001-8525

VL - 2

JO - European clinical respiratory journal

JF - European clinical respiratory journal

IS - 1

M1 - 28517

ER -

Application of nitric oxide measurements in clinical conditions beyond asthma

Abstract

Keywords

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