A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter

M Kleerebezem; OP Kuipers; WM de Vos; ME Stiles; LEN Quadri; Willem M. de Vos; Michael E. Stiles; Luis E.N. Quadri

doi:10.1016/S0196-9781(01)00494-6

A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter

M Kleerebezem, OP Kuipers, WM de Vos, ME Stiles, LEN Quadri^*, Willem M. de Vos, Michael E. Stiles, Luis E.N. Quadri

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

In the lactic acid bacterium Carnobacterium piscicola LV17B a peptide-pheromone dependent quorum-sensing mode is involved in the regulation of bacteriocin production. Bacteriocin CB2 was identified as an environmental signal that induces bacteriocin production. Here, we demonstrate that a second 24 amino acid peptide (CS) also induces bacteriocin production. Transcription activation of several carnobacteriocin operons is triggered by CB2 or CS via a two-component signal transduction system composed of CbnK and CbnR. (C) 2001 Elsevier Science Inc. All rights reserved.

Original language	English
Pages (from-to)	1597-1601
Number of pages	5
Journal	Peptides
Volume	22
Issue number	10
DOIs	https://doi.org/10.1016/S0196-9781(01)00494-6
Publication status	Published - Oct-2001

Keywords

bacteriocin
signal transduction
peptide pheromone
regulation
quorum sensing
LACTOBACILLUS-PLANTARUM C-11
GRAM-POSITIVE BACTERIA
IMMUNITY
PROTEIN
LOCUS
OSMOREGULATION
LACTOCOCCUS
EXPRESSION
INDUCTION
SYSTEMS

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@article{313adf99c61e4d369a8395101b285de2,

title = "A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter",

abstract = "In the lactic acid bacterium Carnobacterium piscicola LV17B a peptide-pheromone dependent quorum-sensing mode is involved in the regulation of bacteriocin production. Bacteriocin CB2 was identified as an environmental signal that induces bacteriocin production. Here, we demonstrate that a second 24 amino acid peptide (CS) also induces bacteriocin production. Transcription activation of several carnobacteriocin operons is triggered by CB2 or CS via a two-component signal transduction system composed of CbnK and CbnR. (C) 2001 Elsevier Science Inc. All rights reserved.",

keywords = "bacteriocin, signal transduction, peptide pheromone, regulation, quorum sensing, LACTOBACILLUS-PLANTARUM C-11, GRAM-POSITIVE BACTERIA, IMMUNITY, PROTEIN, LOCUS, OSMOREGULATION, LACTOCOCCUS, EXPRESSION, INDUCTION, SYSTEMS",

author = "M Kleerebezem and OP Kuipers and {de Vos}, WM and ME Stiles and LEN Quadri and Vos, {Willem M. de} and Stiles, {Michael E.} and Quadri, {Luis E.N.}",

year = "2001",

month = oct,

doi = "10.1016/S0196-9781(01)00494-6",

language = "English",

volume = "22",

pages = "1597--1601",

journal = "Peptides",

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publisher = "ELSEVIER SCIENCE INC",

number = "10",

}

TY - JOUR

T1 - A two-component signal-transduction cascade in Carnobacterium piscicola LV17B

T2 - two signaling peptides and one sensor-transmitter

AU - Kleerebezem, M

AU - Kuipers, OP

AU - de Vos, WM

AU - Stiles, ME

AU - Quadri, LEN

AU - Vos, Willem M. de

AU - Stiles, Michael E.

AU - Quadri, Luis E.N.

PY - 2001/10

Y1 - 2001/10

N2 - In the lactic acid bacterium Carnobacterium piscicola LV17B a peptide-pheromone dependent quorum-sensing mode is involved in the regulation of bacteriocin production. Bacteriocin CB2 was identified as an environmental signal that induces bacteriocin production. Here, we demonstrate that a second 24 amino acid peptide (CS) also induces bacteriocin production. Transcription activation of several carnobacteriocin operons is triggered by CB2 or CS via a two-component signal transduction system composed of CbnK and CbnR. (C) 2001 Elsevier Science Inc. All rights reserved.

AB - In the lactic acid bacterium Carnobacterium piscicola LV17B a peptide-pheromone dependent quorum-sensing mode is involved in the regulation of bacteriocin production. Bacteriocin CB2 was identified as an environmental signal that induces bacteriocin production. Here, we demonstrate that a second 24 amino acid peptide (CS) also induces bacteriocin production. Transcription activation of several carnobacteriocin operons is triggered by CB2 or CS via a two-component signal transduction system composed of CbnK and CbnR. (C) 2001 Elsevier Science Inc. All rights reserved.

KW - bacteriocin

KW - signal transduction

KW - peptide pheromone

KW - regulation

KW - quorum sensing

KW - LACTOBACILLUS-PLANTARUM C-11

KW - GRAM-POSITIVE BACTERIA

KW - IMMUNITY

KW - PROTEIN

KW - LOCUS

KW - OSMOREGULATION

KW - LACTOCOCCUS

KW - EXPRESSION

KW - INDUCTION

KW - SYSTEMS

U2 - 10.1016/S0196-9781(01)00494-6

DO - 10.1016/S0196-9781(01)00494-6

M3 - Article

SN - 0196-9781

VL - 22

SP - 1597

EP - 1601

JO - Peptides

JF - Peptides

IS - 10

ER -

A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter

Abstract

Keywords

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