A mathematical description of nerve fiber bundle trajectories and their variability in the human retina

N. M. Jansonius; J. Nevalainen; B. Selig; L. M. Zangwill; P. A. Sample; W. M. Budde; J. B. Jonas; W. A. Lagreze; P. J. Airaksinen; R. Vonthein; L. A. Levin; J. Paetzold; U. Schiefer

doi:10.1016/j.visres.2009.04.029

A mathematical description of nerve fiber bundle trajectories and their variability in the human retina

N. M. Jansonius^*, J. Nevalainen, B. Selig, L. M. Zangwill, P. A. Sample, W. M. Budde, J. B. Jonas, W. A. Lagreze, P. J. Airaksinen, R. Vonthein, L. A. Levin, J. Paetzold, U. Schiefer

^*Corresponding author for this work

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Abstract

We developed a mathematical model wherein retinal nerve fiber trajectories can be described and the corresponding inter-subject variability analyzed. The model was based on traced nerve fiber bundle trajectories extracted from 55 fundus photographs of 55 human subjects. The model resembled the typical retinal nerve fiber layer course within 20 degrees eccentricity. Depending on the location of the visual field test point, the standard deviation of the calculated corresponding angular location at the optic nerve head circumference ranged from less than 1 degrees to 18 degrees, with an average of 8.8 degrees. (C) 2009 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	2157-2163
Number of pages	7
Journal	Vision Research
Volume	49
Issue number	17
DOIs	https://doi.org/10.1016/j.visres.2009.04.029
Publication status	Published - 28-Aug-2009

Keywords

Glaucoma
Neuro-ophthalmology
Perimetry
Optic nerve head
OPTICAL COHERENCE TOMOGRAPHY
VISUAL-FIELD LOSS
LAYER THICKNESS
GLAUCOMA
HEAD
EYES
ELLIPSOMETRY
PHOTOGRAPHY

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Jansonius, N. M., Nevalainen, J., Selig, B., Zangwill, L. M., Sample, P. A., Budde, W. M., Jonas, J. B., Lagreze, W. A., Airaksinen, P. J., Vonthein, R., Levin, L. A., Paetzold, J., & Schiefer, U. (2009). A mathematical description of nerve fiber bundle trajectories and their variability in the human retina. Vision Research, 49(17), 2157-2163. https://doi.org/10.1016/j.visres.2009.04.029

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title = "A mathematical description of nerve fiber bundle trajectories and their variability in the human retina",

abstract = "We developed a mathematical model wherein retinal nerve fiber trajectories can be described and the corresponding inter-subject variability analyzed. The model was based on traced nerve fiber bundle trajectories extracted from 55 fundus photographs of 55 human subjects. The model resembled the typical retinal nerve fiber layer course within 20 degrees eccentricity. Depending on the location of the visual field test point, the standard deviation of the calculated corresponding angular location at the optic nerve head circumference ranged from less than 1 degrees to 18 degrees, with an average of 8.8 degrees. (C) 2009 Elsevier Ltd. All rights reserved.",

keywords = "Glaucoma, Neuro-ophthalmology, Perimetry, Optic nerve head, OPTICAL COHERENCE TOMOGRAPHY, VISUAL-FIELD LOSS, LAYER THICKNESS, GLAUCOMA, HEAD, EYES, ELLIPSOMETRY, PHOTOGRAPHY",

author = "Jansonius, {N. M.} and J. Nevalainen and B. Selig and Zangwill, {L. M.} and Sample, {P. A.} and Budde, {W. M.} and Jonas, {J. B.} and Lagreze, {W. A.} and Airaksinen, {P. J.} and R. Vonthein and Levin, {L. A.} and J. Paetzold and U. Schiefer",

year = "2009",

month = aug,

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doi = "10.1016/j.visres.2009.04.029",

language = "English",

volume = "49",

pages = "2157--2163",

journal = "Vision Research",

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Jansonius, NM, Nevalainen, J, Selig, B, Zangwill, LM, Sample, PA, Budde, WM, Jonas, JB, Lagreze, WA, Airaksinen, PJ, Vonthein, R, Levin, LA, Paetzold, J & Schiefer, U 2009, 'A mathematical description of nerve fiber bundle trajectories and their variability in the human retina', Vision Research, vol. 49, no. 17, pp. 2157-2163. https://doi.org/10.1016/j.visres.2009.04.029

TY - JOUR

T1 - A mathematical description of nerve fiber bundle trajectories and their variability in the human retina

AU - Jansonius, N. M.

AU - Nevalainen, J.

AU - Selig, B.

AU - Zangwill, L. M.

AU - Sample, P. A.

AU - Budde, W. M.

AU - Jonas, J. B.

AU - Lagreze, W. A.

AU - Airaksinen, P. J.

AU - Vonthein, R.

AU - Levin, L. A.

AU - Paetzold, J.

AU - Schiefer, U.

PY - 2009/8/28

Y1 - 2009/8/28

N2 - We developed a mathematical model wherein retinal nerve fiber trajectories can be described and the corresponding inter-subject variability analyzed. The model was based on traced nerve fiber bundle trajectories extracted from 55 fundus photographs of 55 human subjects. The model resembled the typical retinal nerve fiber layer course within 20 degrees eccentricity. Depending on the location of the visual field test point, the standard deviation of the calculated corresponding angular location at the optic nerve head circumference ranged from less than 1 degrees to 18 degrees, with an average of 8.8 degrees. (C) 2009 Elsevier Ltd. All rights reserved.

AB - We developed a mathematical model wherein retinal nerve fiber trajectories can be described and the corresponding inter-subject variability analyzed. The model was based on traced nerve fiber bundle trajectories extracted from 55 fundus photographs of 55 human subjects. The model resembled the typical retinal nerve fiber layer course within 20 degrees eccentricity. Depending on the location of the visual field test point, the standard deviation of the calculated corresponding angular location at the optic nerve head circumference ranged from less than 1 degrees to 18 degrees, with an average of 8.8 degrees. (C) 2009 Elsevier Ltd. All rights reserved.

KW - Glaucoma

KW - Neuro-ophthalmology

KW - Perimetry

KW - Optic nerve head

KW - OPTICAL COHERENCE TOMOGRAPHY

KW - VISUAL-FIELD LOSS

KW - LAYER THICKNESS

KW - GLAUCOMA

KW - HEAD

KW - EYES

KW - ELLIPSOMETRY

KW - PHOTOGRAPHY

U2 - 10.1016/j.visres.2009.04.029

DO - 10.1016/j.visres.2009.04.029

M3 - Article

SN - 0042-6989

VL - 49

SP - 2157

EP - 2163

JO - Vision Research

JF - Vision Research

IS - 17

ER -

A mathematical description of nerve fiber bundle trajectories and their variability in the human retina

Abstract

Keywords

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