Eleven grants in Impact Explorer for unexpected discoveries

Description

While doing research, one can sometimes run into unexpected results. Even though it was not part of the research plan, you still want to do something with is. So, in order to explore these results, eleven projects will receive a small top-up grant of maximum 30,000 euros.

With this extra budget researchers can create a societal impact. Knowledge utilisation is important for modern science, but is being considered difficult in practice. When sudden opportunities arise, it is beneficial for society if they can be seized. Knowledge utilization increases the chance of societal impact of research and is therefore an important part of NWO's strategy.

Researchers interested in applying for the Impact Explorer can submit a proposal in the ongoing call. The grant is intended for activities to validate the potential societal impact of discoveries from more curiosity-driven research, from the Talent Line and Open Competitions of both NWO and ZonMw and to explore a route towards it. A total of 1 million euro is available for small grants between 20 and 30 thousand euros. A concise procedure will be used during the application process.

Awarded projects:

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• Sensitive detection of circulating proliferating cancer cells – prof. dr. G. van den Bogaart (RUG)

  Following treatment of blood or metastatic cancers, small numbers of cancer cells can remain in the body, which is called minimal residual disease (MRD). MRD is the main cause of cancer relapse, and the number of circulating proliferating cancer cells correlates with patient outcome for several (blood) cancer types. However, current MRD tests are complex and testing is not yet routine clinical practice. We developed a technique for detecting dividing cells in blood samples that is more sensitive, specific, and cost-effective than existing assays. Funding from NWO is requested to assess the impact of the technique on MRD detection and diagnostics. Together with the Technology Transfer Office of Groningen University, we will collaborate on a market report, roadmap development, funding strategies, and network and partnership strategy. Literature review, desk research, and consulting external experts will inform the assessment of the assay's viability and plan for in vitro diagnostics (IVD) development.

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